Description
Description
Combining high capacity, ion-exchange Mustang membranes with a unique 16-layer open-pleat design results in a high-flow rate, high capacity, single-use, versatile range of pleated products that can be used for a wide range of applications.
This 16-layer construction is held constant from the laboratory-scale Mustang XT Acrodisc Unit to the largest industrial process-scale capsule, ensuring constant chromatography bed depth in all formats. Mustang E capsules use three layers of a standard pleat format membrane to remove endotoxin from process feedstreams. The three-layer construction is held constant from the Mustang E Acrodisc® format to the largest industrial process scale capsule.
The ease of linear scale-up ensures a shortened process development time by significantly reducing the re-optimization required between scale-up steps. These chromatography products are specifically designed for single-use. This eliminates cleaning and the costs associated with cleaning validation. Mustang capsules are fully self-contained units that connect directly into a system using 18 mm (1.5 in.) sanitary flange connectors. Mustang cartridges require the use of a Code 7 housing, which requires cleaning and reassembly after each use.
Mustang Q Membrane
Mustang Q membrane is anion-exchange support with pendant quaternary amine functional groups in a cross-linked polymeric coating on a 0.8-micron pore-size membrane. This gives high dynamic capacities for high molecular weight products such as DNA, plasmids, or even particles as large as viruses.
Mustang S Membrane
Mustang S membrane is cation-exchange support with pendant sulfonic functional groups in a cross-linked polymeric coating on a 0.65 µm pore-size membrane. This gives high dynamic capacities for high molecular weight products such as IgG, Factor VIII, and some viruses.
Mustang E Membrane
Mustang E membrane is a highly cross-linked quaternized amine charge polymer coating on a 0.2-micron pore size membrane. This gives very high dynamic capacities under selected conditions for removing the endotoxin from process feedstreams, buffers, and water.
Specification
Note:
For CLxMST*P1, x =
M05 for a Q, S or E unit with a bed volume of 10 mL
3 for a Q or S unit with a bed volume of 60 mL or an E unit with a bed volume of 40 mL
For NPxMSTG*P1, x =
6 for a Q or S unit with a bed volume of 260 mL or an E unit with a bed volume of 160 mL
7 for a Q or S unit with a bed volume of 520 mL or an E unit with a bed volume of 320 mL
8 for a Q or S unit with a bed volume of 780 mL or an E unit with a bed volume of 480 mL
* =
Q for a unit with Q (quaternary amine) chemistry membrane
S for a unit with S (sulfonic acid) chemistry membrane
E for a unit with E (polyethyleneimine) chemistry membrane
