Description
The Allegro XRS 25 bioreactor system is a single-use bioreactor system with unique agitation and control properties designed for the cultivation of mammalian cells in suspension culture under controlled conditions. It is suitable for applications ranging from general life sciences research to seed train operations and full cGMP production at the 2 to 25 L scale.

The mixing properties of the 3D biocontainer bag design and bi-axial agitation lead to superior cell culture performance in mammalian suspension systems. With faster delivery of nutrients to the cellular micro-environment (and faster removal of metabolites), the Allegro XRS 25 bioreactor system allows cells to attain higher densities, with higher overall viabilities, leading to significantly higher protein expression levels.
The excellent mixing properties of the Allegro XRS 25 bioreactor system have also shown to be beneficial for growing batch, fed batch and perfusion cultures of mammalian (CHO, hybridoma) and insect cells.

Allegro XRS 25 bioreactor system – featuring the agitation platform, the single-use biocontainer and the mPath™ control tower with mPath Link supervisory control and data acquisition (SCADA) software package. The Allegro XRS 25 bioreactor system incorporates many features to ensure easy operation, robust performance, and suitability for cGMP operations.
Because of its unique bi-axial agitation and the subsequent shorter mixing times and higher mass transfer properties, the Allegro XRS 25 bioreactor system produces superior performance compared to competitor rocker systems, as measured by higher density, better cell viability, and higher expression levels.
The Allegro XRS 25 bioreactor system is available as a standard product; however, both the bioreactor hardware and consumables can be customized. Our teams are specialized in upstream and downstream processing and will gladly help find the right technology for any part of your manufacturing process. It is possible to combine the Allegro products to meet any requirement in the upstream part of the process:
Media preparation
Buffer preparation
Media sterilization and aseptic transfer
Liquid transfer into the bioreactor (e.g. glucose, anti-foam, base, etc.)
Seed train solutions
Cell harvest and separation






